Deletion of the NSm Virulence Gene of Rift Valley Fever Virus Inhibits Virus Replication in and Dissemination from the Midgut of Aedes aegypti Mosquitoes

Deletion of the NSm Virulence Gene of Rift Valley Fever Virus Inhibits Virus Replication in and Dissemination from the Midgut of Aedes aegypti Mosquitoes

Rift Valley fever virus (RVFV) is a mosquito-borne virus endemic to Africa. Outbreaks of RVFV have resulted in devastating morbidity and mortality in livestock and humans. A novel RVFV vaccine strain has been developed in which two virulence genes, NSs and NSm, have been deleted from the RVFV genome...

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Bibliographic Details
Main Authors: Kading, Rebekah C., Crabtree, Mary B., Bird, Brian H., Nichol, Stuart T., Erickson, Bobbie Rae, Horiuchi, Kalanthe, Biggerstaff, Brad J., Miller, Barry R.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923680/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923680/

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