Rab11 facilitates cross-talk between autophagy and endosomal pathway through regulation of Hook localization
This study shows that the small GTPase Rab11 is required for both autophagosome and endosome maturation. The authors demonstrate a novel cross-talk mechanism through which autophagy can orchestrate endosomal maturation events to ensure the required endolysosomal input for autophagosome maturation.
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
The American Society for Cell Biology
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923643/ |