Nuclear Morphometric Analysis of Leydig Cells of Male Pubertal Rats Exposed In Utero to Di(n-butyl) Phthalate

We recently reported that prenatal rat exposure to di(n-butyl) phthalate (DBP) induced Leydig cell (LC) hyperplasia after nine weeks (wks) of age, yet the number of LCs was similar to that of the vehicle group until seven weeks. Nuclear pleomorphism of hyperplastic LCs is common and is considered t...

Full description

Bibliographic Details
Main Authors: Wakui, Shin, Motohashi, Masaya, Satoh, Takemi, Shirai, Masaru, Mutou, Tomoko, Takahashi, Hiroyuki, Wempe, Michael F., Endou, Hitoshi, Inomata, Tomoo, Asari, Masao
Format: Online
Language:English
Published: Japanese Society of Toxicologic Pathology 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921929/