De Novo Reconstruction of Consensus Master Genomes of Plant RNA and DNA Viruses from siRNAs

Virus-infected plants accumulate abundant, 21–24 nucleotide viral siRNAs which are generated by the evolutionary conserved RNA interference (RNAi) machinery that regulates gene expression and defends against invasive nucleic acids. Here we show that, similar to RNA viruses, the entire genome sequenc...

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Bibliographic Details
Main Authors: Seguin, Jonathan, Rajeswaran, Rajendran, Malpica-López, Nachelli, Martin, Robert R., Kasschau, Kristin, Dolja, Valerian V., Otten, Patricia, Farinelli, Laurent, Pooggin, Mikhail M.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921208/