Sodium 4-phenylbutyrate suppresses the development of dextran sulfate sodium-induced colitis in mice

Sodium 4-phenylbutyrate suppresses the development of dextran sulfate sodium-induced colitis in mice

Sodium 4-phenylbutyrate (PBA) exhibits anti-inflammatory effects by suppressing nuclear factor-κB (NF-κB) activation. In the present study, the effects of PBA on a mouse model of dextran sulfate sodium (DSS)-induced colitis were investigated. The therapeutic efficacy of PBA (150 mg/kg body weight) i...

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Bibliographic Details
Main Authors: ONO, KAZUHIKO, NIMURA, SATOSHI, NISHINAKAGAWA, TAKUYA, HIDESHIMA, YUKO, ENJYOJI, MUNECHIKA, NABESHIMA, KAZUKI, NAKASHIMA, MANABU
Format: Online
Language:English
Published: D.A. Spandidos 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919895/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919895/

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