PennSeq: accurate isoform-specific gene expression quantification in RNA-Seq by modeling non-uniform read distribution

PennSeq: accurate isoform-specific gene expression quantification in RNA-Seq by modeling non-uniform read distribution

Correctly estimating isoform-specific gene expression is important for understanding complicated biological mechanisms and for mapping disease susceptibility genes. However, estimating isoform-specific gene expression is challenging because various biases present in RNA-Seq (RNA sequencing) data com...

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Bibliographic Details
Main Authors: Hu, Yu, Liu, Yichuan, Mao, Xianyun, Jia, Cheng, Ferguson, Jane F., Xue, Chenyi, Reilly, Muredach P., Li, Hongzhe, Li, Mingyao
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919567/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919567/

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