Towards accurate structural characterization of metal centres in protein crystals: the structures of Ni and Cu T6 bovine insulin derivatives

The level of structural detail around the metal sites in Ni2+ and Cu2+ T6 insulin derivatives was significantly improved by using a combination of single-crystal X-ray crystallography and X-ray absorption spectroscopy. Photoreduction and subsequent radiation damage of the Cu2+ sites in Cu insulin wa...

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Bibliographic Details
Main Authors: Frankaer, Christian Grundahl, Mossin, Susanne, Ståhl, Kenny, Harris, Pernille
Format: Online
Language:English
Published: International Union of Crystallography 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919263/