Dabrafenib for treatment of BRAF-mutant melanoma
Melanoma has the highest mortality of all the skin cancer subtypes. Historically, chemotherapy and immunologic therapies have yielded only modest results in the treatment of metastatic melanoma. The discovery of prevalent V600 BRAF mutations driving proliferation makes this oncogenic protein an idea...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Dove Medical Press
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917541/ |