Diverse functions of matrix metalloproteinases during fibrosis

Fibrosis – a debilitating condition that can occur in most organs – is characterized by excess deposition of a collagen-rich extracellular matrix (ECM). At first sight, the activities of proteinases that can degrade matrix, such as matrix metalloproteinases (MMPs), might be expected to be under-expr...

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Bibliographic Details
Main Authors: Giannandrea, Matthew, Parks, William C.
Format: Online
Language:English
Published: The Company of Biologists Limited 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917240/