Automated Detection of Synapses in Serial Section Transmission Electron Microscopy Image Stacks

We describe a method for fully automated detection of chemical synapses in serial electron microscopy images with highly anisotropic axial and lateral resolution, such as images taken on transmission electron microscopes. Our pipeline starts from classification of the pixels based on 3D pixel featur...

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Bibliographic Details
Main Authors: Kreshuk, Anna, Koethe, Ullrich, Pax, Elizabeth, Bock, Davi D., Hamprecht, Fred A.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916342/