Construction of a Novel Liver-Targeting Fusion Interferon by Incorporation of a Plasmodium Region I-Plus Peptide

Interferon alpha (IFN α) exerts a multiplicity of biological actions including antiviral, immunomodulatory, and antiproliferative effects. Administration of IFN α is the current treatment for chronic hepatitis B; however, therapy outcome has not been completely satisfactory. The systemic effects of...

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Bibliographic Details
Main Authors: Lu, Xuemei, Jin, Xiaobao, Huang, Yanting, Wang, Jie, Shen, Juan, Chu, Fujiang, Mei, Hanfang, Ma, Yan, Zhu, Jiayong
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915749/