Characterization of Human CD39+ Th17 Cells with Suppressor Activity and Modulation in Inflammatory Bowel Disease

Induced regulatory T-cells (iT-reg) and T helper type 17 (Th17) in the mouse share common CD4 progenitor cells and exhibit overlapping phenotypic and functional features. Here, we show that human Th17 cells endowed with suppressor activity (supTh17) can be derived following exposure of iT-reg popula...

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Bibliographic Details
Main Authors: Longhi, Maria Serena, Moss, Alan, Bai, Aiping, Wu, Yan, Huang, Huang, Cheifetz, Adam, Quintana, Francisco J., Robson, Simon C.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914873/