Digital-Direct-RT-PCR: a sensitive and specific method for quantification of CTC in patients with cervical carcinoma

The detection of circulating tumour cells (CTC) in cancer patients may be useful for therapy monitoring and prediction of relapse. A sensitive assay based on HPV-oncogene transcripts which are highly specific for cervical cancer cells was established. The Digital-Direct-RT-PCR (DD-RT-PCR) combines F...

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Bibliographic Details
Main Authors: Pfitzner, Claudia, Schröder, Isabel, Scheungraber, Cornelia, Dogan, Askin, Runnebaum, Ingo Bernhard, Dürst, Matthias, Häfner, Norman
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913920/