Liposomes coated with thiolated chitosan enhance oral peptide delivery to rats☆

The aim of the present study was the in vivo evaluation of thiomer-coated liposomes for an oral application of peptides. For this purpose, salmon calcitonin was chosen as a model drug and encapsulated within liposomes. Subsequently, the drug loaded liposomes were coated with either chitosan–thioglyc...

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Bibliographic Details
Main Authors: Gradauer, K., Barthelmes, J., Vonach, C., Almer, G., Mangge, H., Teubl, B., Roblegg, E., Dünnhaupt, S., Fröhlich, E., Bernkop-Schnürch, A., Prassl, R.
Format: Online
Language:English
Published: Elsevier Science Publishers 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913890/