Caveolin-1 Is a Critical Determinant of Autophagy, Metabolic Switching, and Oxidative Stress in Vascular Endothelium

Caveolin-1 is a scaffolding/regulatory protein that interacts with diverse signaling molecules. Caveolin-1null mice have marked metabolic abnormalities, yet the underlying molecular mechanisms are incompletely understood. We found the redox stress plasma biomarker plasma 8-isoprostane was elevated i...

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Bibliographic Details
Main Authors: Shiroto, Takashi, Romero, Natalia, Sugiyama, Toru, Sartoretto, Juliano L., Kalwa, Hermann, Yan, Zhonghua, Shimokawa, Hiroaki, Michel, Thomas
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912129/