Modulation of mitochondrial bioenergetics in a skeletal muscle cell line model of mitochondrial toxicity☆

Mitochondrial toxicity is increasingly being implicated as a contributing factor to many xenobiotic-induced organ toxicities, including skeletal muscle toxicity. This has necessitated the need for predictive in vitro models that are able to sensitively detect mitochondrial toxicity of chemical entit...

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Bibliographic Details
Main Authors: Dott, William, Mistry, Pratibha, Wright, Jayne, Cain, Kelvin, Herbert, Karl E
Format: Online
Language:English
Published: Elsevier 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909783/