Pharmacological and therapeutic potential of Cordyceps with special reference to Cordycepin
An entomopathogenic fungus, Cordyceps sp. has been known to have numerous pharmacological and therapeutic implications, especially, in terms of human health making it a suitable candidate for ethno-pharmacological use. Main constituent of the extract derived from this fungus comprises a novel bio-me...
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2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909570/ |
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pubmed-39095702014-02-06 Pharmacological and therapeutic potential of Cordyceps with special reference to Cordycepin Tuli, Hardeep S. Sandhu, Sardul S. Sharma, A. K. Review Article An entomopathogenic fungus, Cordyceps sp. has been known to have numerous pharmacological and therapeutic implications, especially, in terms of human health making it a suitable candidate for ethno-pharmacological use. Main constituent of the extract derived from this fungus comprises a novel bio-metabolite called as Cordycepin (3′deoxyadenosine) which has a very potent anti-cancer, anti-oxidant and anti-inflammatory activities. The current review discusses about the broad spectrum potential of Cordycepin including biological and pharmacological actions in immunological, hepatic, renal, cardiovascular systems as well as an anti-cancer agent. The article also reviews the current efforts to delineate the mechanism of action of Cordycepin in various bio-molecular processes. The study will certainly draw the attention of scientific community to improve the bioactivity and production of Cordycepin for its commercial use in pharmacological and medical fields. Springer Berlin Heidelberg 2013-02-19 2014-02 /pmc/articles/PMC3909570/ /pubmed/28324458 http://dx.doi.org/10.1007/s13205-013-0121-9 Text en © The Author(s) 2013 Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Tuli, Hardeep S. Sandhu, Sardul S. Sharma, A. K. |
spellingShingle |
Tuli, Hardeep S. Sandhu, Sardul S. Sharma, A. K. Pharmacological and therapeutic potential of Cordyceps with special reference to Cordycepin |
author_facet |
Tuli, Hardeep S. Sandhu, Sardul S. Sharma, A. K. |
author_sort |
Tuli, Hardeep S. |
title |
Pharmacological and therapeutic potential of Cordyceps with special reference to Cordycepin |
title_short |
Pharmacological and therapeutic potential of Cordyceps with special reference to Cordycepin |
title_full |
Pharmacological and therapeutic potential of Cordyceps with special reference to Cordycepin |
title_fullStr |
Pharmacological and therapeutic potential of Cordyceps with special reference to Cordycepin |
title_full_unstemmed |
Pharmacological and therapeutic potential of Cordyceps with special reference to Cordycepin |
title_sort |
pharmacological and therapeutic potential of cordyceps with special reference to cordycepin |
description |
An entomopathogenic fungus, Cordyceps sp. has been known to have numerous pharmacological and therapeutic implications, especially, in terms of human health making it a suitable candidate for ethno-pharmacological use. Main constituent of the extract derived from this fungus comprises a novel bio-metabolite called as Cordycepin (3′deoxyadenosine) which has a very potent anti-cancer, anti-oxidant and anti-inflammatory activities. The current review discusses about the broad spectrum potential of Cordycepin including biological and pharmacological actions in immunological, hepatic, renal, cardiovascular systems as well as an anti-cancer agent. The article also reviews the current efforts to delineate the mechanism of action of Cordycepin in various bio-molecular processes. The study will certainly draw the attention of scientific community to improve the bioactivity and production of Cordycepin for its commercial use in pharmacological and medical fields. |
publisher |
Springer Berlin Heidelberg |
publishDate |
2013 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909570/ |
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1612053714550390784 |