A Single Sfp-Type Phosphopantetheinyl Transferase Plays a Major Role in the Biosynthesis of PKS and NRPS Derived Metabolites in Streptomyces ambofaciens ATCC23877

The phosphopantetheinyl transferases (PPTases) are responsible for the activation of the carrier protein domains of the polyketide synthases (PKS), non ribosomal peptide synthases (NRPS) and fatty acid synthases (FAS). The analysis of the Streptomyces ambofaciens ATCC23877 genome has revealed the pr...

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Bibliographic Details
Main Authors: Bunet, Robert, Riclea, Ramona, Laureti, Luisa, Hôtel, Laurence, Paris, Cédric, Girardet, Jean-Michel, Spiteller, Dieter, Dickschat, Jeroen S., Leblond, Pierre, Aigle, Bertrand
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909215/