Phosphatase Complex Pph3/Psy2 Is Involved in Regulation of Efficient Non-Homologous End-Joining Pathway in the Yeast Saccharomyces cerevisiae

One of the main mechanisms for double stranded DNA break (DSB) repair is through the non-homologous end-joining (NHEJ) pathway. Using plasmid and chromosomal repair assays, we showed that deletion mutant strains for interacting proteins Pph3p and Psy2p had reduced efficiencies in NHEJ. We further ob...

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Bibliographic Details
Main Authors: Omidi, Katayoun, Hooshyar, Mohsen, Jessulat, Matthew, Samanfar, Bahram, Sanders, Megan, Burnside, Daniel, Pitre, Sylvain, Schoenrock, Andrew, Xu, Jianhua, Babu, Mohan, Golshani, Ashkan
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909046/