An In Silico Approach for Modelling T-Helper Polarizing iNKT Cell Agonists

An In Silico Approach for Modelling T-Helper Polarizing iNKT Cell Agonists

Many analogues of the glycolipid alpha-galactosylceramide (α-GalCer) are known to activate iNKT cells through their interaction with CD1d-expressing antigen-presenting cells, inducing the release of Th1 and Th2 cytokines. Because of iNKT cell involvement and associated Th1/Th2 cytokine changes in a...

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Bibliographic Details
Main Authors: De Spiegeleer, Anton, Wynendaele, Evelien, Vandekerckhove, Matthias, Stalmans, Sofie, Boucart, Maxime, Van Den Noortgate, Nele, Venken, Koen, Van Calenbergh, Serge, Aspeslagh, Sandrine, Elewaut, Dirk
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909045/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909045/

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