Protein-driven inference of miRNA–disease associations

Motivation: MicroRNAs (miRNAs) are a highly abundant class of non-coding RNA genes involved in cellular regulation and thus also diseases. Despite miRNAs being important disease factors, miRNA–disease associations remain low in number and of variable reliability. Furthermore, existing databases and...

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Main Authors:	Mørk, Søren, Pletscher-Frankild, Sune, Palleja Caro, Albert, Gorodkin, Jan, Jensen, Lars Juhl
Format:	Online
Language:	English
Published:	Oxford University Press 2014
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904518/

id	pubmed-3904518
recordtype	oai_dc
spelling	pubmed-39045182014-01-28 Protein-driven inference of miRNA–disease associations Mørk, Søren Pletscher-Frankild, Sune Palleja Caro, Albert Gorodkin, Jan Jensen, Lars Juhl Original Papers Motivation: MicroRNAs (miRNAs) are a highly abundant class of non-coding RNA genes involved in cellular regulation and thus also diseases. Despite miRNAs being important disease factors, miRNA–disease associations remain low in number and of variable reliability. Furthermore, existing databases and prediction methods do not explicitly facilitate forming hypotheses about the possible molecular causes of the association, thereby making the path to experimental follow-up longer. Oxford University Press 2014-02-01 2013-11-21 /pmc/articles/PMC3904518/ /pubmed/24273243 http://dx.doi.org/10.1093/bioinformatics/btt677 Text en © The Author 2013. Published by Oxford University Press. http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Mørk, Søren Pletscher-Frankild, Sune Palleja Caro, Albert Gorodkin, Jan Jensen, Lars Juhl
spellingShingle	Mørk, Søren Pletscher-Frankild, Sune Palleja Caro, Albert Gorodkin, Jan Jensen, Lars Juhl Protein-driven inference of miRNA–disease associations
author_facet	Mørk, Søren Pletscher-Frankild, Sune Palleja Caro, Albert Gorodkin, Jan Jensen, Lars Juhl
author_sort	Mørk, Søren
title	Protein-driven inference of miRNA–disease associations
title_short	Protein-driven inference of miRNA–disease associations
title_full	Protein-driven inference of miRNA–disease associations
title_fullStr	Protein-driven inference of miRNA–disease associations
title_full_unstemmed	Protein-driven inference of miRNA–disease associations
title_sort	protein-driven inference of mirna–disease associations
description	Motivation: MicroRNAs (miRNAs) are a highly abundant class of non-coding RNA genes involved in cellular regulation and thus also diseases. Despite miRNAs being important disease factors, miRNA–disease associations remain low in number and of variable reliability. Furthermore, existing databases and prediction methods do not explicitly facilitate forming hypotheses about the possible molecular causes of the association, thereby making the path to experimental follow-up longer.
publisher	Oxford University Press
publishDate	2014
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904518/
_version_	1612052012346638336

Protein-driven inference of miRNA–disease associations

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