Clinical Evaluation of Abiraterone in the Treatment of Metastatic Prostate Cancer

Treatment of castration-resistant prostate cancer remains an area of unmet medical need. Evidence suggests that this entity continues to be driven by androgens and androgen receptor (AR) signaling. Abiraterone acetate, a pregnenolone derivative, is an oral selective and irreversible inhibitor of the...

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Bibliographic Details
Main Authors: Goyal, Jatinder, Antonarakis, Emmanuel S.
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904375/