Protection Against Lethal Marburg Virus Infection Mediated by Lipid Encapsulated Small Interfering RNA

Background. Marburg virus (MARV) infection causes severe morbidity and mortality in humans and nonhuman primates. Currently, there are no licensed therapeutics available for treating MARV infection. Here, we present the in vitro development and in vivo evaluation of lipid-encapsulated small interfer...

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Bibliographic Details
Main Authors: Ursic-Bedoya, Raul, Mire, Chad E., Robbins, Marjorie, Geisbert, Joan B., Judge, Adam, MacLachlan, Ian, Geisbert, Thomas W.
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903369/