An optimized streptavidin-binding RNA aptamer for purification of ribonucleoprotein complexes identifies novel ARE-binding proteins
Determining the composition of messenger ribonucleoprotein (mRNP) particles is essential for a comprehensive understanding of the complex mechanisms underlying mRNA regulation, but is technically challenging. Here we present an RNA-based method to identify RNP components using a modified streptavidi...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902943/ |