The primary microRNA-208b interacts with Polycomb-group protein, Ezh2, to regulate gene expression in the heart
The Polycomb-group protein, Ezh2, is required for epigenetic gene silencing in the adult heart by unknown mechanism. We investigated the role of Ezh2 and non-coding RNAs in a mouse model of pressure overload using transverse aortic constriction (TAC) attenuated by the prototypical histone deacetylas...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902903/ |