Regulation of MYC Expression and Differential JQ1 Sensitivity in Cancer Cells

Regulation of MYC Expression and Differential JQ1 Sensitivity in Cancer Cells

High level MYC expression is associated with almost all human cancers. JQ1, a chemical compound that inhibits MYC expression is therapeutically effective in preclinical animal models in midline carcinoma, and Burkitt’s lymphoma (BL). Here we show that JQ1 does not inhibit MYC expression to a similar...

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Bibliographic Details
Main Authors: Fowler, Trent, Ghatak, Payel, Price, David H., Conaway, Ronald, Conaway, Joan, Chiang, Cheng-Ming, Bradner, James E., Shilatifard, Ali, Roy, Ananda L.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900694/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900694/

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