GTP-dependent run-up of Piezo2-type mechanically activated currents in rat dorsal root ganglion neurons

Rapidly adapting mechanically activated channels (RA) are expressed in primary afferent neurons and identified as Piezo2 ion channels. We made whole-cell voltage-clamp recordings from cultured dorsal root ganglion (DRG) neurons to study RA channel regulation. RA currents showed gradual increases in...

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Bibliographic Details
Main Authors: Jia, Zhanfeng, Ikeda, Ryo, Ling, Jennifer, Gu, Jianguo G
Format: Online
Language:English
Published: BioMed Central 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899620/