Maturation of Induced Pluripotent Stem Cell Derived Hepatocytes by 3D-Culture

Induced pluripotent stem cell derived hepatocytes (IPSC-Heps) have the potential to reduce the demand for a dwindling number of primary cells used in applications ranging from therapeutic cell infusions to in vitro toxicology studies. However, current differentiation protocols and culture methods pr...

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Bibliographic Details
Main Authors: Gieseck III, Richard L., Hannan, Nicholas R. F., Bort, Roque, Hanley, Neil A., Drake, Rosemary A. L., Cameron, Grant W. W., Wynn, Thomas A., Vallier, Ludovic
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899231/