Subunit Positioning and Stator Filament Stiffness in Regulation and Power Transmission in the V1 Motor of the Manduca sexta V-ATPase☆
The vacuolar H+-ATPase (V-ATPase) is an ATP-driven proton pump essential to the function of eukaryotic cells. Its cytoplasmic V1 domain is an ATPase, normally coupled to membrane-bound proton pump Vo via a rotary mechanism. How these asymmetric motors are coupled remains poorly understood. Low energ...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Elsevier
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899036/ |