Cytochrome c oxidase response to changes in cerebral oxygen delivery in the adult brain shows higher brain-specificity than haemoglobin☆

The redox state of cerebral mitochondrial cytochrome c oxidase monitored with near-infrared spectroscopy (Δ[oxCCO]) is a signal with strong potential as a non-invasive, bedside biomarker of cerebral metabolic status. We hypothesised that the higher mitochondrial density of brain compared to skin and...

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Bibliographic Details
Main Authors: Kolyva, Christina, Ghosh, Arnab, Tachtsidis, Ilias, Highton, David, Cooper, Chris E., Smith, Martin, Elwell, Clare E.
Format: Online
Language:English
Published: Academic Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898943/