Spindle Assembly Checkpoint of Oocytes Depends on a Kinetochore Structure Determined by Cohesin in Meiosis I
Since the dissolution of sister chromatid cohesion by separase and cyclin B destruction is irreversible, it is essential to delay both until all chromosomes have bioriented on the mitotic spindle. Kinetochores that are not correctly attached to the spindle generate the mitotic checkpoint complex (MC...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Cell Press
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898714/ |