Fatal Disseminated Mucormycosis in an Immunocompotent Patient: A Case Report and Literature Review

Disseminated mucormycosis is a rare entity most frequently seen in neutropenic patients with hematologic malignancies, post transplants or in patients on deferoxamine therapy. We report a 64-year-old immunocompetent male with an acute pneumonia and a generalized jaundice who died within 24 h. In the...

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Main Authors:	Sarrami, Amir Hossein, Setareh, Mehrdad, Izadinejad, Masoud, Afshar-Moghaddam, Noushin, Baradaran-Mahdavi, Mohammad Mehdi, Meidani, Mohsen
Format:	Online
Language:	English
Published:	Medknow Publications & Media Pvt Ltd 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898454/

id	pubmed-3898454
recordtype	oai_dc
spelling	pubmed-38984542014-02-04 Fatal Disseminated Mucormycosis in an Immunocompotent Patient: A Case Report and Literature Review Sarrami, Amir Hossein Setareh, Mehrdad Izadinejad, Masoud Afshar-Moghaddam, Noushin Baradaran-Mahdavi, Mohammad Mehdi Meidani, Mohsen Case Report Disseminated mucormycosis is a rare entity most frequently seen in neutropenic patients with hematologic malignancies, post transplants or in patients on deferoxamine therapy. We report a 64-year-old immunocompetent male with an acute pneumonia and a generalized jaundice who died within 24 h. In the autopsy, extensive perforations of spleen and multiple hemorrhage foci on the pancreas were two significant findings. Histopathological study of tissue sections revealed typical zygomycetes hyphae in the left lung, pancreas, spleen and brain. Involvement of pancreas in this patient was one of the rare features of mucormycosis reported occasionally in the literature. Our case implies an unusual clinical presentation of disseminated mucormycosis and highlights that disseminated mucormycosis should be regarded even in the immunocompetent patients. Medknow Publications & Media Pvt Ltd 2013-12 /pmc/articles/PMC3898454/ /pubmed/24498504 Text en Copyright: © International Journal of Preventive Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Sarrami, Amir Hossein Setareh, Mehrdad Izadinejad, Masoud Afshar-Moghaddam, Noushin Baradaran-Mahdavi, Mohammad Mehdi Meidani, Mohsen
spellingShingle	Sarrami, Amir Hossein Setareh, Mehrdad Izadinejad, Masoud Afshar-Moghaddam, Noushin Baradaran-Mahdavi, Mohammad Mehdi Meidani, Mohsen Fatal Disseminated Mucormycosis in an Immunocompotent Patient: A Case Report and Literature Review
author_facet	Sarrami, Amir Hossein Setareh, Mehrdad Izadinejad, Masoud Afshar-Moghaddam, Noushin Baradaran-Mahdavi, Mohammad Mehdi Meidani, Mohsen
author_sort	Sarrami, Amir Hossein
title	Fatal Disseminated Mucormycosis in an Immunocompotent Patient: A Case Report and Literature Review
title_short	Fatal Disseminated Mucormycosis in an Immunocompotent Patient: A Case Report and Literature Review
title_full	Fatal Disseminated Mucormycosis in an Immunocompotent Patient: A Case Report and Literature Review
title_fullStr	Fatal Disseminated Mucormycosis in an Immunocompotent Patient: A Case Report and Literature Review
title_full_unstemmed	Fatal Disseminated Mucormycosis in an Immunocompotent Patient: A Case Report and Literature Review
title_sort	fatal disseminated mucormycosis in an immunocompotent patient: a case report and literature review
description	Disseminated mucormycosis is a rare entity most frequently seen in neutropenic patients with hematologic malignancies, post transplants or in patients on deferoxamine therapy. We report a 64-year-old immunocompetent male with an acute pneumonia and a generalized jaundice who died within 24 h. In the autopsy, extensive perforations of spleen and multiple hemorrhage foci on the pancreas were two significant findings. Histopathological study of tissue sections revealed typical zygomycetes hyphae in the left lung, pancreas, spleen and brain. Involvement of pancreas in this patient was one of the rare features of mucormycosis reported occasionally in the literature. Our case implies an unusual clinical presentation of disseminated mucormycosis and highlights that disseminated mucormycosis should be regarded even in the immunocompetent patients.
publisher	Medknow Publications & Media Pvt Ltd
publishDate	2013
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898454/
_version_	1612049990111199232

Fatal Disseminated Mucormycosis in an Immunocompotent Patient: A Case Report and Literature Review

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