A Role for Topographic Cues in the Organization of Collagenous Matrix by Corneal Fibroblasts and Stem Cells

Human corneal fibroblasts (HCF) and corneal stromal stem cells (CSSC) each secrete and organize a thick stroma-like extracellular matrix in response to different substrata, but neither cell type organizes matrix on tissue-culture polystyrene. This study compared cell differentiation and extracellula...

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Bibliographic Details
Main Authors: Karamichos, Dimitrios, Funderburgh, Martha L., Hutcheon, Audrey E. K., Zieske, James D., Du, Yiqin, Wu, Jian, Funderburgh, James L.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897697/