Genetic variations in Toll-like receptors (TLRs 3/7/8) are associated with systemic lupus erythematosus in a Taiwanese population

Toll-like receptors (TLRs), as innate immunity sensors, play critical roles in immune responses. Six SNPs of TLR3, TLR7, and TLR8 were genotyped to determine their associations with systemic lupus erythematosus (SLE) and clinical manifestations of SLE. TLR7 SNP rs3853839 was independently associated...

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Bibliographic Details
Main Authors: Wang, Chin-Man, Chang, Su-Wei, Wu, Yeong-Jian Jan, Lin, Jing-Chi, Ho, Huei-Huang, Chou, Tse-Chih, Yang, Bing, Wu, Jianming, Chen, Ji-Yih
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896912/