Validation of nucleolar protein 4 as a novel methylated tumor suppressor gene in head and neck cancer

Methylation of CpG islands in the promoter region of genes acts as a significant mechanism of epigenetic gene silencing in head and neck cancer. In the present study, we assessed the association of epigenetic alterations of a panel of 12 genes [nucleolar protein 4 (NOL4), iroquois homeobox 1 (IRX1),...

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Bibliographic Details
Main Authors: DEMOKAN, SEMRA, CHUANG, ALICE Y., PATTANI, KAVITA M., SIDRANSKY, DAVID, KOCH, WAYNE, CALIFANO, JOSEPH A.
Format: Online
Language:English
Published: D.A. Spandidos 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896520/