Validation of nucleolar protein 4 as a novel methylated tumor suppressor gene in head and neck cancer
Methylation of CpG islands in the promoter region of genes acts as a significant mechanism of epigenetic gene silencing in head and neck cancer. In the present study, we assessed the association of epigenetic alterations of a panel of 12 genes [nucleolar protein 4 (NOL4), iroquois homeobox 1 (IRX1),...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
D.A. Spandidos
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896520/ |