The difluoromethylene (CF2) group in aliphatic chains: Synthesis and conformational preference of palmitic acids and nonadecane containing CF2 groups

The syntheses of palmitic acids and a nonadecane are reported with CF2 groups located 1,3 or 1,4 to each other along the aliphatic chain. Specifically 8,8,10,10- and 8,8,11,11-tetrafluorohexadecanoic acids (6b and 6c) are prepared as well as the singly modified analogue 8,8-difluorohexadecanoic acid...

Full description

Bibliographic Details
Main Authors: Wang, Yi, Callejo, Ricardo, Slawin, Alexandra M Z, O’Hagan, David
Format: Online
Language:English
Published: Beilstein-Institut 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896246/