Angiopoietin-Like Protein 2 Induced by Mechanical Stress Accelerates Degeneration and Hypertrophy of the Ligamentum Flavum in Lumbar Spinal Canal Stenosis

Angiopoietin-Like Protein 2 Induced by Mechanical Stress Accelerates Degeneration and Hypertrophy of the Ligamentum Flavum in Lumbar Spinal Canal Stenosis

Chronic inflammation and subsequent fibrosis induced by mechanical stress play an important role in ligamentum flavum (LF) hypertrophy and degeneration in patients with lumbar spinal canal stenosis (LSCS). Angiopoietin-like protein 2 (Angptl2) is a chronic inflammatory mediator induced under various...

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Bibliographic Details
Main Authors: Nakamura, Takayuki, Okada, Tatsuya, Endo, Motoyoshi, Kadomatsu, Tsuyoshi, Taniwaki, Takuya, Sei, Akira, Odagiri, Haruki, Masuda, Tetsuro, Fujimoto, Toru, Nakamura, Takafumi, Oike, Yuichi, Mizuta, Hiroshi
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894965/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894965/

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