L-dopa-induced dyskinesia: beyond an excessive dopamine tone in the striatum

L-dopa-induced dyskinesia: beyond an excessive dopamine tone in the striatum

L-dopa remains the mainstay treatment for Parkinson's disease (PD), although in later stages, treatment is complicated by L-dopa-induced dyskinesias (LID). Current evidence links LID to excessive striatal L-dopa-derived dopamine (DA) release, while the possibility of a direct involvement of L-d...

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Main Authors: Porras, Gregory, De Deurwaerdere, Philippe, Li, Qin, Marti, Matteo, Morgenstern, Rudolf, Sohr, Reinhard, Bezard, Erwan, Morari, Michele, Meissner, Wassilios G.
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893648/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893648/

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