Bone resorption is regulated by cell-autonomous negative feedback loop of Stat5–Dusp axis in the osteoclast
The transcription factor Stat5 inhibits the bone-resorbing function of osteoclasts, in part by inducing the expression of the phosphatases Dusp1 and Dusp2.
Main Authors: | , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892975/ |