A Bayesian Hierarchical Model for Relating Multiple SNPs within Multiple Genes to Disease Risk

A variety of methods have been proposed for studying the association of multiple genes thought to be involved in a common pathway for a particular disease. Here, we present an extension of a Bayesian hierarchical modeling strategy that allows for multiple SNPs within each gene, with external prior i...

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Bibliographic Details
Main Authors: Duan, Lewei, Thomas, Duncan C.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892936/