A Flagellin-Derived Toll-Like Receptor 5 Agonist Stimulates Cytotoxic Lymphocyte-Mediated Tumor Immunity

Toll-like receptor (TLR) mediated recognition of pathogen associated molecular patterns allows the immune system to rapidly respond to a pathogenic insult. The “danger context” elicited by TLR agonists allows an initially non-immunogenic antigen to become immunogenic. This ability to alter environme...

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Bibliographic Details
Main Authors: Leigh, Nicholas D., Bian, Guanglin, Ding, Xilai, Liu, Hong, Aygun-Sunar, Semra, Burdelya, Lyudmila G., Gudkov, Andrei V., Cao, Xuefang
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891810/