Chemical Suppression of Defects in Mitotic Spindle Assembly, Redox Control, and Sterol Biosynthesis by Hydroxyurea
We describe the results of a systematic search for a class of hitherto-overlooked chemical-genetic interactions in the Saccharomyces cerevisiae genome, which exists between a detrimental genetic mutation and a chemical/drug that can ameliorate, rather than exacerbate, that detriment. We refer to thi...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Genetics Society of America
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887538/ |