Disruption of blood-brain barrier in Alzheimer disease pathogenesis

Blood-brain barrier (BBB) regulates transport of various molecules and maintains brain homeostasis. Perturbed intracellular Ca2+ homeostasis and BBB damage have been implicated in the pathogenesis of Alzheimer disease (AD). Although receptor for advanced glycation end products (RAGE) is known to med...

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Bibliographic Details
Main Authors: Kook, Sun-Young, Seok Hong, Hyun, Moon, Minho, Mook-Jung, Inhee
Format: Online
Language:English
Published: Landes Bioscience 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887048/