Effects of Aggregatibacter actinomycetemcomitans leukotoxin on endothelial cells☆

Aggregatibacter actinomycetemcomitans is a human pathogen that produces leukotoxin (LtxA) as a major virulence factor. In this study the effect of LtxA on microvascular endothelial cell viability and phenotype was studied. High doses of single LtxA treatment (500 ng/ml to 5 μg/ml) significantly and...

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Bibliographic Details
Main Authors: Dietmann, Anelia, Millonig, Alban, Combes, Valery, Couraud, Pierre-Olivier, Kachlany, Scott C., Grau, Georges E.
Format: Online
Language:English
Published: Academic Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885975/