Effects of Aggregatibacter actinomycetemcomitans leukotoxin on endothelial cells☆
Aggregatibacter actinomycetemcomitans is a human pathogen that produces leukotoxin (LtxA) as a major virulence factor. In this study the effect of LtxA on microvascular endothelial cell viability and phenotype was studied. High doses of single LtxA treatment (500 ng/ml to 5 μg/ml) significantly and...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
Academic Press
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885975/ |