Ovarian Cancer Spheroid Cells with Stem Cell-Like Properties Contribute to Tumor Generation, Metastasis and Chemotherapy Resistance through Hypoxia-Resistant Metabolism

Ovarian Cancer Spheroid Cells with Stem Cell-Like Properties Contribute to Tumor Generation, Metastasis and Chemotherapy Resistance through Hypoxia-Resistant Metabolism

Cells with sphere forming capacity, spheroid cells, are present in the malignant ascites of patients with epithelial ovarian cancer (EOC) and represent a significant impediment to efficacious treatment due to their putative role in progression, metastasis and chemotherapy resistance. The exact mecha...

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Bibliographic Details
Main Authors: Liao, Jianqun, Qian, Feng, Tchabo, Nana, Mhawech-Fauceglia, Paulette, Beck, Amy, Qian, Zikun, Wang, Xinhui, Huss, Wendy J., Lele, Shashikant B., Morrison, Carl D., Odunsi, Kunle
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883678/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883678/

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