Effect of Insulin on ACE2 Activity and Kidney Function in the Non-Obese Diabetic Mouse

We studied the non-obese diabetic (NOD) mice model because it develops autoimmune diabetes that resembles human type 1 diabetes. In diabetic mice, urinary albumin excretion (UAE) was ten-fold increased at an “early stage” of diabetes, and twenty-fold increased at a “later stage” (21 and 40 days, res...

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Bibliographic Details
Main Authors: Riera, Marta, Márquez, Eva, Clotet, Sergi, Gimeno, Javier, Roca-Ho, Heleia, Lloreta, Josep, Juanpere, Nuria, Batlle, Daniel, Pascual, Julio, Soler, María José
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882249/