Matrix Stiffness Affects Endocytic Uptake of MK2-Inhibitor Peptides

In this study, the role of substrate stiffness on the endocytic uptake of a cell-penetrating peptide was investigated. The cell-penetrating peptide, an inhibitor of mitogen-activated protein kinase activated protein kinase II (MK2), enters a primary mesothelial cell line predominantly through caveol...

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Bibliographic Details
Main Authors: Brugnano, Jamie L., Panitch, Alyssa
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882240/