Caenorhabditis elegans as a model system for studying non-cell-autonomous mechanisms in protein-misfolding diseases
Caenorhabditis elegans has a number of distinct advantages that are useful for understanding the basis for cellular and organismal dysfunction underlying age-associated diseases of protein misfolding. Although protein aggregation, a key feature of human neurodegenerative diseases, has been typically...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
The Company of Biologists Limited
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882046/ |