Clinical Marker of Platelet Hyperreactivity in Diabetes Mellitus
Atherothrombotic complications are important causes of morbidity and mortality in diabetic patients. Diabetes has been considered to be a prothrombotic status. Several factors contribute to the prothrombotic condition, such as increasing coagulation, impaired fibrinolysis, endothelial dysfunction, a...
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Korean Diabetes Association
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881326/ |
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pubmed-38813262014-01-08 Clinical Marker of Platelet Hyperreactivity in Diabetes Mellitus Kim, Jin Hwa Bae, Hak Yeon Kim, Sang Yong Review Atherothrombotic complications are important causes of morbidity and mortality in diabetic patients. Diabetes has been considered to be a prothrombotic status. Several factors contribute to the prothrombotic condition, such as increasing coagulation, impaired fibrinolysis, endothelial dysfunction, and platelet hyperreactivity. Among the factors that contribute to the prothrombotic status in diabetes, altered platelet function plays a crucial role. Although understanding platelet function abnormalities in diabetes still remains as a challenge, more attention should be focused on platelet function for effective management and the prediction of atherothrombotic events in diabetic patients. This review will provide an overview on the current status of knowledge of platelet function abnormalities and clinical marker of platelet hyperreactivity in patients with diabetes. Korean Diabetes Association 2013-12 2013-12-12 /pmc/articles/PMC3881326/ /pubmed/24404513 http://dx.doi.org/10.4093/dmj.2013.37.6.423 Text en Copyright © 2013 Korean Diabetes Association http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Kim, Jin Hwa Bae, Hak Yeon Kim, Sang Yong |
| spellingShingle |
Kim, Jin Hwa Bae, Hak Yeon Kim, Sang Yong Clinical Marker of Platelet Hyperreactivity in Diabetes Mellitus |
| author_facet |
Kim, Jin Hwa Bae, Hak Yeon Kim, Sang Yong |
| author_sort |
Kim, Jin Hwa |
| title |
Clinical Marker of Platelet Hyperreactivity in Diabetes Mellitus |
| title_short |
Clinical Marker of Platelet Hyperreactivity in Diabetes Mellitus |
| title_full |
Clinical Marker of Platelet Hyperreactivity in Diabetes Mellitus |
| title_fullStr |
Clinical Marker of Platelet Hyperreactivity in Diabetes Mellitus |
| title_full_unstemmed |
Clinical Marker of Platelet Hyperreactivity in Diabetes Mellitus |
| title_sort |
clinical marker of platelet hyperreactivity in diabetes mellitus |
| description |
Atherothrombotic complications are important causes of morbidity and mortality in diabetic patients. Diabetes has been considered to be a prothrombotic status. Several factors contribute to the prothrombotic condition, such as increasing coagulation, impaired fibrinolysis, endothelial dysfunction, and platelet hyperreactivity. Among the factors that contribute to the prothrombotic status in diabetes, altered platelet function plays a crucial role. Although understanding platelet function abnormalities in diabetes still remains as a challenge, more attention should be focused on platelet function for effective management and the prediction of atherothrombotic events in diabetic patients. This review will provide an overview on the current status of knowledge of platelet function abnormalities and clinical marker of platelet hyperreactivity in patients with diabetes. |
| publisher |
Korean Diabetes Association |
| publishDate |
2013 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881326/ |
| _version_ |
1612044415221628928 |