A Role for FACT in Repopulation of Nucleosomes at Inducible Genes

Xenobiotic drugs induce Pleiotropic Drug Resistance (PDR) genes via the orthologous Pdr1/Pdr3 transcription activators. We previously identified the Mediator transcription co-activator complex as a key target of Pdr1 orthologs and demonstrated that Pdr1 interacts directly with the Gal11/Med15 subuni...

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Bibliographic Details
Main Authors: Voth, Warren P., Takahata, Shinya, Nishikawa, Joy L., Metcalfe, Benjamin M., Näär, Anders M., Stillman, David J.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879260/